PIPA520985

TCTN3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520985-Each-of-1 In Stock ₹ 46,502.50

PIPA520985 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TCTN3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TCTN3

Gene Alias

4930521E07Rik; AI197391; C10orf61; JBTS18; OFD4; PSEC0041; RGD1305166; RP11-7D5.3; TCTN3; Tect3; tectonic 3; tectonic family member 3; tectonic-3; UNQ1881/PRO4324

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26123, 309486, 67590

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q6NUS6, Q8R2Q6

Gene Symbols

TCTN3

Immunogen

A 17 amino acid peptide near the carboxy terminus of human TCTN3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is SK-N-SH cell lysate
  • PA5-20985 can be used with blocking peptide PEP-1099
  • TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube
  • While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1
  • TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node
  • Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator
  • At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.