PIPA521007

CRISP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521007-Each-of-1 In Stock ₹ 46,502.50

PIPA521007 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CRISP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CRISP2

Gene Alias

Cancer/testis antigen 36; CRISP2; CRISP-2; Crisp2l; CT36; cysteine rich secretory protein 2; cysteine-rich secretory protein 2; cysteine-rich secretory protein 2-like; GAPDL5; glyceraldehyde-3-phosphate dehydrogenase-like 5; MGC111136; OTTHUMP00000016589; testicular tissue protein Li 43; testis specific gene 1; testis specific protein 1; testis specific protein 1 (probe H4-1 p3-1); testis-specific protein TPX-1; TPX1; Tpx-1; TSP1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7180

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P16562

Gene Symbols

CRISP2

Immunogen

A 15 amino acid peptide near the amino terminus of human CRISP2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human testis tissue lysate
  • PA5-21007 can be used with blocking peptide PEP-1121
  • The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility
  • CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion
  • CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility
  • CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.