NALP4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521020-Each-of-1 | In Stock | ₹ 47,481.50 |
PIPA521020 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
NALP4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLRP4
Gene Alias
4930406H16Rik; cancer/testis antigen 58; CLR19.5; CT58; E330021B02; E330028A19Rik; NACHT, leucine rich repeat and PYD containing 4; NACHT, leucine rich repeat and PYD containing 4A; NACHT, leucine rich repeat and PYD containing 4E; NACHT, LRR and PYD containing protein 4; NACHT, LRR and PYD domains-containing protein 4; NACHT, LRR and PYD domains-containing protein 4A; NACHT, LRR and PYD domains-containing protein 4E; NACHT/LRR/pyrin domain-containing protein 4; NALP, epsilon; NALP4; Nalp4a; Nalp4e; NALP-epsilon; Nalp-eta; Nalp-ita; NLR family pyrin domain containing 4; NLR family, pyrin domain containing 4; NLR family, pyrin domain containing 4A; NLR family, pyrin domain containing 4E; Nlrp4; Nlrp4a; Nlrp4e; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 4; PAAD and NACHT-containing protein 2; PAN2; PYPAF4; PYRIN and NACHT-containing protein 2; PYRIN-containing APAF1-like protein 4; RGD1561918; RGD1563529; Ribonuclease inhibitor 2; RNH2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
147945, 243880, 446099
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q66X19, Q8BU40, Q96MN2
Gene Symbols
NLRP4, Nlrp4a, Nlrp4e
Immunogen
A 13 amino acid peptide near the center of human NALP4.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is K562 cell lysate
- PA5-21020 can be used with blocking peptide PEP-1134
- NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction
- NALP4, also known as PYRIN-containing APAF1-like protein 4, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain
- In transfected 293 cells, NALP4 suppressed NF-kappa-B induction by TNF-a and IL-1-b, suggesting NALP4 operates at a point of convergence in these two signaling pathways
- NALP4 also suppressed NF-kappa-B induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways, including TRAF2, TRAF6, RIP, and IRAK2, as well as the IKK-alpha and IKK-beta, suggesting that NALP4 is critical in modulating NF-kappa-B activity.