NALP7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521023-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA521023 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
NALP7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NLRP7
Gene Alias
CLR19.4; HYDM; NACHT, leucine rich repeat and PYD containing 7; NACHT, LRR and PYD containing protein 7; NACHT, LRR and PYD domains-containing protein 7; NALP7; NLR family pyrin domain containing 7; NLR family, pyrin domain containing 7; NLRP7; NOD12; Nucleotide-binding oligomerization domain protein 12; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7; PAN7; PYPAF3; PYRIN-containing APAF1-like protein 3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
199713
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q8WX94
Gene Symbols
NLRP7
Immunogen
An 18 amino acid peptide near the amino terminus of human NALP7.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is human brain tissue lysate
- PA5-21023 can be used with blocking peptide PEP-1137
- NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins
- NALP7, also known as PYPAF3, a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation
- NALP7 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain
- It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain
- NALP7 inhibits caspase-1-dependent interleukin-1-b secretion and is a feedback regulator of interleukin-1-b secretion
- Defects in the NALP7 gene are known to cause the formation of a hydatidiform mole (HYDM) and reduce the growth of carcinoma cell lines.