PIPA521049

MFSD2A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521049-Each-of-1 In Stock ₹ 49,528.50

PIPA521049 - Each of 1

₹ 49,528.50

In Stock

Quantity

1

Base Price: ₹ 49,528.50

GST (18%): ₹ 8,915.13

Total Price: ₹ 58,443.63

Antigen

MFSD2A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MFSD2A

Gene Alias

1700018O18Rik; HMFN0656; major facilitator superfamily domain containing 2; major facilitator superfamily domain containing 2A; major facilitator superfamily domain-containing protein 2A; MCPH15; MFSD2; MFSD2A; NLS1; PP9177; RGD1310174; sodium-dependent LPC symporter 1; sodium-dependent lysophosphatidylcholine symporter 1; UNQ300/PRO341; zgc:101615

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

298504, 76574, 84879

Content And Storage

4° C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q8NA29, Q9DA75

Gene Symbols

MFSD2A

Immunogen

An 18 amino acid peptide near the carboxy terminus of human MFSD2A.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is rat lung tissue lysate
  • PA5-21049 can be used with blocking peptide PEP-1163
  • Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs
  • Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific
  • MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts
  • MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting
  • The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.