LIF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521122-Each-of-1 | In Stock | ₹ 49,617.50 |
PIPA521122 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,617.50
GST (18%): ₹ 8,931.15
Total Price: ₹ 58,548.65
Antigen
LIF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Lif
Gene Alias
CDF; cholinergic differentiation factor; cholinergic neuronal differentiation factor; d factor; DIA; differentiation inhibitory activity; differentiation-inducing factor; differentiation-stimulating factor; Emfilermin; hepatocyte-stimulating factor III; HILDA; human interleukin in DA cells; leukemia inhibitory factor; leukemia inhibitory factor (cholinergic differentiation factor); LIF; Melanoma-derived LPL inhibitor; MLPLI; myeloid leukaemia inhibitory factor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16878, 3976, 60584
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P09056, P15018, P17777
Gene Symbols
Lif
Immunogen
A 16 amino acid peptide near the center of human LIF.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is EL4 cell lysate
- PA5-21122 can be used with blocking peptide PEP-1236
- Leukemia inhibitory factor (LIF) is a 20 kDa protein that belongs to the IL-6 receptor family
- It binds to a heterodimeric membrane receptor made up of a LIF-specific subunit, gp190 or LIFR, and the subunit gp130, which is shared with the other members of the IL-6 family
- LIF expression has been observed in various tissues including thymus, lung, and neuronal tissue
- LIF can be up-regulated by pro-inflammatory cytokines such as TNFα and IL-17, and elevated levels of LIF have been found in cases of rheumatoid arthritis, neural injury, systemic inflammation, and tuberculosis
- LIF displays diverse biological effects, but is best known for its ability to inhibit the differentiation of embryonic stem cells in mice and contribute to stem cell self-renewal.Human and mouse LIF share 79% sequence homology and exhibit cross-species activity
- However, LIF inhibition of stem cell differentiation appears to be mouse-specific.