PIPA520892

GATA3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520892-Each-of-1 In Stock ₹ 49,528.50

PIPA520892 - Each of 1

₹ 49,528.50

In Stock

Quantity

1

Base Price: ₹ 49,528.50

GST (18%): ₹ 8,915.13

Total Price: ₹ 58,443.63

Antigen

GATA3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GATA3

Gene Alias

EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14462, 2625, 85471

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

ChIP Assay, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

P23771, P23772

Gene Symbols

GATA3

Immunogen

A 17 amino acid peptide near the carboxy terminus of human GATA3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human brain tissue lysate
  • PA5-20892 can be used with blocking peptide PEP-1006
  • The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins
  • Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes
  • GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain
  • GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages
  • GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers
  • Labastie et al
  • (1994) cloned the human gene and the 5-prime end of the mouse gene
  • The human gene comprises 6 exons distributed over 17 kb of DNA
  • Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.