NUMB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521143-Each-of-1 | In Stock | ₹ 46,769.50 |
PIPA521143 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,769.50
GST (18%): ₹ 8,418.51
Total Price: ₹ 55,188.01
Antigen
NUMB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Numb
Gene Alias
c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18222, 29419, 8650
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
P49757, Q2LC84, Q9QZS3
Gene Symbols
Numb
Immunogen
A 17 amino acid peptide near the carboxy terminus of human NUMB.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse lung tissue lysate
- PA5-21143 can be used with blocking peptide PEP-1257
- Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells
- Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex
- NUMB is also expressed in postmitotic neurons and plays a role in axonal growth
- Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.