ATRX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521348-Each-of-1 | In Stock | ₹ 51,976.00 |
PIPA521348 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,976.00
GST (18%): ₹ 9,355.68
Total Price: ₹ 61,331.68
Antigen
ATRX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATRX
Gene Alias
4833408C14Rik; AI447451; alpha thalassemia/mental retardation syndrome (X-linked); alpha thalassemia/mental retardation syndrome X-linked; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae); alpha thalassemia/mental retardation syndrome X-linked homolog; alpha thalassemia/mental retardation syndrome X-linked homolog (human); ATP-dependent helicase ATRX; ATR2; ATRX; ATRX, chromatin remodeler; DNA dependent ATPase and helicase; DXHXS6677E; helicase 2; helicase 2, X-linked; helicase II; heterochromatin protein 2; HP1 alpha-interacting protein; Hp1bp2; Hp1bp38; HP1-BP38; HP1-BP38 protein; JMS; mental retardation, X-linked 52; MRX52; MRXHF1; MRXS3; pABP-2; Rad54; RAD54L; RP5-875J14.1; SFM1; SHS; transcriptional regulator ATRX; XH2; X-linked helicase II; X-linked nuclear protein; XNP; Zinc finger helicase; Znf-HX
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22589, 246284, 546
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.27 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
P46100, P70486, Q61687
Gene Symbols
ATRX
Immunogen
Recombinant fragment corresponding to a region within amino acids 2161 and 2443 of Rad54 (Uniprot ID#P46100)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, HeLa, HepG2, NIH3T3, PC-12, Rat-2
- Predicted reactivity: Mouse (97%), Chimpanzee (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- ATRX encodes a protein that contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins
- The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome
- These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes
- This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis
- Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.