A-Raf Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521354-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA521354 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
A-Raf
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARAF
Gene Alias
1200013E08Rik; Araf; A-RAF; A-Raf proto-oncogene serine/threonine-protein kinase; A-Raf proto-oncogene, serine/threonine kinase; Araf1; A-raf-1; AW495444; Oncogene ARAF1; PKS; PKS2; Proto-oncogene A-Raf; proto-oncogene A-Raf-1; Proto-oncogene Pks; raf a; Raf related protein; RAFA1; raf-related oncogene; Ras-binding protein; Ras-binding protein DA-Raf; RP1-230G1.1; serine/threonine-protein kinase A-Raf; v-raf murine sarcoma 3611 viral oncogene homolog; v-raf murine sarcoma 3611 viral oncogene homolog 1; v-raf murine sarcoma 3611 viral oncogene-like protein; v-raf oncogene homolog 1 (murine sarcoma 3611 virus)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11836, 369
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.85 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P04627, P10398
Gene Symbols
ARAF
Immunogen
Recombinant fragment corresponding to a region within amino acids 371 and 554 of A-RAF (Uniprot ID#P10398)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3
- Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (85%), Xenopus laevis (86%), Pig (99%), Sheep (99%), Bovine (99%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways
- These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1
- Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity
- It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus
- The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain
- A-Raf, a second member of the Raf gene family of serine/ threonine protein kinases, exhibits substantial homology to Raf-1 within the kinase domain of the two molecules, but less homology elsewhere
- Expression of A-Raf is found at highest levels in urogenital tissues and kidney and at lowest level in brain tissue.