PSMA7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521379-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA521379 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PSMA7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PSMA7
Gene Alias
C6; C6-I; epididymis secretory protein Li 276; HEL-S-276; HSPC; proteasome (prosome, macropain) subunit, alpha type 7; proteasome (prosome, macropain) subunit, alpha type, 7; proteasome subunit alpha 4; proteasome subunit alpha 7; proteasome subunit alpha type-7; Proteasome subunit RC6-1; proteasome subunit XAPC7; Psma7; RC6-1; RP5-1005F21.4; testicular tissue protein Li 151; XAPC7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26444, 5688
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.32 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O14818, Q9Z2U0
Gene Symbols
PSMA7
Immunogen
Recombinant fragment corresponding to a region within amino acids 10 and 247 of Proteasome 20S alpha 7 (Uniprot ID#O14818)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain
- Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (97%), Pig (98%), Chicken (96%), Bovine (99%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins
- This complex plays numerous essential roles within the cell by associating with different regulatory particles
- Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins
- The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required
- Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation
- This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
- Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions
- The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions
- Plays a role in hepatitis C virus internal ribosome entry site-mediated translation
- Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation.