PIPA521411

PUF60 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521411-Each-of-1 In Stock ₹ 53,044.00

PIPA521411 - Each of 1

₹ 53,044.00

In Stock

Quantity

1

Base Price: ₹ 53,044.00

GST (18%): ₹ 9,547.92

Total Price: ₹ 62,591.92

Antigen

PUF60

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Puf60

Gene Alias

2410104I19Rik; 2810454F19Rik; 60 kDa poly(U)-binding-splicing factor; FBP interacting repressor; FBP-interacting repressor; FIR; FLJ31379; FUSE-binding protein-interacting repressor; LOW QUALITY PROTEIN: poly(U)-binding-splicing factor PUF60; poly(U) binding splicing factor 60; poly(U) binding splicing factor 60KDa; poly(U)-binding-splicing factor PUF60; poly-U binding splicing factor 60; poly-U binding splicing factor 60K; poly-U binding splicing factor 60KDa; PUF60; pyrimidine tract binding splicing factor; RNA-binding protein Siah-BP; Ro ribonucleoprotein-binding protein 1; Ro-binding protein 1; RoBP1; ROBPI; Siah binding protein 1; siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1; siah-binding protein 1; SIAHBP1; Siah-BP1; similar to fuse-binding protein-interacting repressor isoform a; VRJS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22827, 67959

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.81 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q3UEB3, Q9UHX1

Gene Symbols

Puf60

Immunogen

Recombinant protein fragment contain a sequence corresponding to a region within amino acids 346 and 523 (Q9UHX1) of PUF60

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, H1299, HeLaS3, HepG2, Molt-4, Raji
  • Predicted reactivity: Mouse (98%), Rat (98%), Bovine (98%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • PUF60 encodes a protein that is a Ro RNP-binding protein
  • It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs
  • This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein
  • It can repress a c-myc reporter via the FUSE
  • It is also known to target transcription factor IIH and inhibit activated transcription
  • This gene is implicated in the xeroderma pigmentosum disorder
  • There are two alternatively spliced transcript variants of this gene encoding different isoforms
  • There seems to be evidence of multiple polyadenylation sites for this gene.