BMP-10 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA521940-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA521940 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
BMP-10
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BMP10
Gene Alias
BMP; BMP10; BMP-10; bmp10 {ECO:0000312; bmp10b; Bone morphogenetic protein; bone morphogenetic protein 10; EMBL:BAE16990.1, ECO:0000312; RGD:1562986}; si:dkey-13n15.5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
27302
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.51 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O95393
Gene Symbols
BMP10
Immunogen
Synthetic peptide corresponding to a region within amino acids 360 and 424 of BMP10 (Uniprot ID#O95393)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: H1299
- Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins
- Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life
- BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation
- It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6
- The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes
- BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration.