PIPA524018

MYCT1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA524018-Each-of-1 In Stock ₹ 46,502.50

PIPA524018 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MYCT1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Myct1

Gene Alias

1110020B04Rik; AI225941; AI642973; MTLC; MTMC1; MT-MC1; myc target 1; myc target in myeloid cells 1; myc target in myeloid cells protein 1; Myc target protein 1; Myct1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

80177

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q8N699

Gene Symbols

Myct1

Immunogen

KLH conjugated synthetic peptide between 135-163 amino acids from the C-terminal region of human MYCT1

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells
  • It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation
  • MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes
  • RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.