Importin 9 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA525477-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA525477 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
Importin 9
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IPO9
Gene Alias
0710008K06Rik; AI845704; C78347; DKFZp761M1547; FLJ10402; HSPC273; Imp9; imp9a; imp9b; importin 9; importin-9; importin-9a; importin-9b; Ipo9; KIAA1192; mKIAA1192; Ran binding protein 9; ran-binding protein 9; RANBP9; RP11-90L20.4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
226432, 55705
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q91YE6, Q96P70
Gene Symbols
IPO9
Immunogen
KLH conjugated synthetic peptide between 79-106 amino acids from the N-terminal region of human IPO9
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Functions in nuclear protein import as nuclear transport receptor
- Serves as receptor for nuclear localization signals (NLS) in cargo substrates
- Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism
- At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran
- The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus
- Mediates the nuclear import of H2B histone, RPS7 and RPL18A
- Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains
- May also import H2A, H3, H4 histones, RPL4 and RPL6.