PIPA525538
CPEB4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA525538-Each-of-1 | In Stock | ₹ 47,926.50 |
PIPA525538 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,926.50
GST (18%): ₹ 8,626.77
Total Price: ₹ 56,553.27
Antigen
CPEB4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CPEB4
Gene Alias
CPEB4; Cpeb-4; CPE-binding protein 4; Cpe-bp4; cytoplasmic polyadenylation element binding protein 4; cytoplasmic polyadenylation element-binding protein 4; hCPEB-4; KIAA1673; mCPEB-4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
67579, 80315
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q17RY0, Q7TN98
Gene Symbols
CPEB4
Immunogen
KLH conjugated synthetic peptide between 109-137 amino acids from the N-terminal region of human CPEB4
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR (PubMed:24990967)
- RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967)
- Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited
- Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195)
- Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752)
- Stimulates proliferation of melanocytes (PubMed:27857118)
- In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory
- [UniProt]