C4BPA Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA525861-Each-of-1 | In Stock | ₹ 48,816.50 |
PIPA525861 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,816.50
GST (18%): ₹ 8,786.97
Total Price: ₹ 57,603.47
Antigen
C4BPA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
C4BPA
Gene Alias
AI195242; C4b-binding protein; C4b-binding protein alpha chain; C4bp; C4bpa; complement component 4 binding protein; complement component 4 binding protein alpha; complement component 4 binding protein, alpha; proline-rich protein; PRP; RP11-164O23.4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
722
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P04003
Gene Symbols
C4BPA
Immunogen
KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human C4BPA
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- There are 3 variants of Complement component 4 binding protein (C4bp), which is composed of alpha and beta chains
- The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain
- The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain
- C4bp regulates the activation of the classical complement pathway
- It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b
- C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a
- Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S
- C4bp is expressed in the blood serum.