KIR2DL2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA525666-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA525666 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
KIR2DL2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KIR2DL2
Gene Alias
CD158 antigen-like family member B1; CD158b; CD158B1; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2; killer cell immunoglobulin-like receptor 2DL2; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2; KIR2DL2; MHC class I NK cell receptor; natural killer cell receptor; natural killer-associated transcript 6; NKAT6; NKAT-6; p58 natural killer cell receptor clone CL-43; p58 NK receptor CL-43; p58.2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3803
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P43627
Gene Symbols
KIR2DL2
Immunogen
KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human KIR2DL2
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells
- The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC)
- The gene content of the KIR gene cluster varies among haplotypes, although several "eframework"e genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2)
- The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain
- KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals
- The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.