PIPA526323

GPX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA526323-Each-of-1 In Stock ₹ 48,816.50

PIPA526323 - Each of 1

₹ 48,816.50

In Stock

Quantity

1

Base Price: ₹ 48,816.50

GST (18%): ₹ 8,786.97

Total Price: ₹ 57,603.47

Antigen

GPX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GPX1

Gene Alias

AI195024; AL033363; Cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase; glutathione peroxidase 1; Gpx; Gpx1; GPx-1; GPXD; GSHPx; GSHPX1; GSHPx-1; HGNC:4553; MGC14399; MGC88245; OTTHUMP00000210766; Selenium-dependent glutathione peroxidase 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14775, 2876

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2.0 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P07203, P11352

Gene Symbols

GPX1

Immunogen

KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human GPX1

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

Ig

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Description

  • Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione
  • There are several isoforms which differ in their primary structure and localization
  • The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered
  • GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract
  • Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation
  • Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine
  • All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.