PIPA526331
DAGLB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA526331-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA526331 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
DAGLB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DAGLB
Gene Alias
DAGLB; DAGLBETA; DGL-beta; diacylglycerol lipase beta; diacylglycerol lipase, beta; E330036I19Rik; KCCR13L; RGD1310193; sn1-specific diacylglycerol lipase beta
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
221955, 231871
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Western Blot
Concentration
0.4 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q8NCG7, Q91WC9
Gene Symbols
DAGLB
Immunogen
KLH conjugated synthetic peptide between 491-518 amino acids from the central region of human DAGLB
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Lipase that catalyzes the hydrolysis of arachidonic acid (AA)-esterified diacylglycerols (DAGs) to produce the principal endocannabinoid, 2-arachidonoylglycerol (2-AG) which can be further cleaved by downstream enzymes to release arachidonic acid (AA) for cyclooxygenase (COX)-mediated eicosanoid production (PubMed:14610053)
- Preferentially hydrolyzes DAGs at the sn-1 position in a calcium-dependent manner and has negligible activity against other lipids including monoacylglycerols and phospholipids (PubMed:14610053)
- Plays a key role in the regulation of 2-AG and AA pools utilized by COX1/2 to generate lipid mediators of macrophage and microglia inflammatory responses
- Functions also as a polyunsaturated fatty acids-specific triacylglycerol lipase in macrophages
- Plays an important role to support the metabolic and signaling demands of macrophages
- [UniProt]