PIPA524727

Epiregulin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA524727-Each-of-1 In Stock ₹ 50,952.50

PIPA524727 - Each of 1

₹ 50,952.50

In Stock

Quantity

1

Base Price: ₹ 50,952.50

GST (18%): ₹ 9,171.45

Total Price: ₹ 60,123.95

Antigen

Epiregulin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ereg

Gene Alias

Ep; Epiregulin; EPR; ER; EREG; Proepiregulin

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2069

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

O14944

Gene Symbols

Ereg

Immunogen

KLH conjugated synthetic peptide between 137-165 amino acids from the C-terminal region of human EREG

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3
  • It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and colon
  • Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells
  • It also inhibits the growth of several tumor-derived epithelial cell lines
  • Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.