PIPA527073

GRPR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527073-Each-of-1 In Stock ₹ 46,502.50

PIPA527073 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

GRPR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRPR

Gene Alias

BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14829, 24938, 2925

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P21729, P30550, P52500

Gene Symbols

GRPR

Immunogen

Synthetic peptide corresponding to a region within amino acids 200 and 294 of Human GRPR

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HeLaS3, Molt-4, mouse pancreas, mouse brain, rat brain, rat pancreas
  • Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues
  • The effects of GRP are mediated through the gastrin-releasing peptide receptor
  • This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway
  • The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate
  • An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.