PIPA526791

GRPR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA526791-Each-of-1 In Stock ₹ 48,816.50

PIPA526791 - Each of 1

₹ 48,816.50

In Stock

Quantity

1

Base Price: ₹ 48,816.50

GST (18%): ₹ 8,786.97

Total Price: ₹ 57,603.47

Antigen

GRPR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GRPR

Gene Alias

BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2925

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P30550

Gene Symbols

GRPR

Immunogen

KLH conjugated synthetic peptide between 123-152 amino acids from the central region of human GRPR

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with mouse and rat based on sequence homology
  • Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues
  • The effects of GRP are mediated through the gastrin-releasing peptide receptor
  • This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway
  • The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate
  • An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.