ACVRL1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527081-Each-of-1 | In Stock | ₹ 45,968.50 |
PIPA527081 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,968.50
GST (18%): ₹ 8,274.33
Total Price: ₹ 54,242.83
Antigen
ACVRL1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ACVRL1
Gene Alias
activin A receptor like type 1, activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor like kinase 1, activin receptor-like kinase 1, activin receptor-like kinase-1, Acvrl1, Acvrlk1, AI115505, AI427544, ALK1, ALK-1, HHT, HHT2, ORW2, R3, R-3, Serine/threonine-protein kinase receptor R3, SETHKIR, SKR3, TGF-B superfamily receptor type I, TSR-I
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11482, 94
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P37023, Q61288
Gene Symbols
ACVRL1
Immunogen
Synthetic peptide corresponding to a region within amino acids 441 and 503 of Human Activin A Receptor Type II-like 1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, 293T mem, HepG2, HepG2 mem, BCL-1
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands
- ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail
- Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2
- Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.