E2F1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527365-Each-of-1 | In Stock | ₹ 48,193.50 |
PIPA527365 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,193.50
GST (18%): ₹ 8,674.83
Total Price: ₹ 56,868.33
Antigen
E2F1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
E2F1
Gene Alias
E2F transcription factor 1; E2F1; E2F-1; mKIAA4009; PBR3; PRB-binding protein E2F-1; RBAP1; RBAP-1; RBBP3; RBBP-3; RBP3; Retinoblastoma-associated protein 1; retinoblastoma-binding protein 3; Transcription factor E2F1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1869
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q01094
Gene Symbols
E2F1
Immunogen
Recombinant fragment corresponding to a region within amino acids 43 and 217 of Human E2F1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, NIH-3T3, E2F1-transfected 293T
- Predicted reactivity: Mouse (96%), Rat (97%), Chicken (86%), Bovine (96%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The protein encoded by this gene is a member of the E2F family of transcription factors
- The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
- The E2F proteins contain several evolutionally conserved domains found in most members of the family
- These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
- This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain
- This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner
- It can mediate both cell proliferation and p53-dependent/independent apoptosis.