Septin 2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527485-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA527485 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
Septin 2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SEPTIN2
Gene Alias
2-Sep; AW208991; DIFF6; hNedd5; KIAA0158; mKIAA0158; NEDD5; Nedd-5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed, developmentally down-regulated gene 5; Pnutl3; Sept2; septin 2; Septin2; septin-2; Vascular endothelial cell specific protein 11; Vesp11
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18000, 4735
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P42208, Q15019
Gene Symbols
SEPTIN2
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 175 of Human Septin 2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: NT2D1, IMR32, Jurkat, HeLa
- Predicted reactivity: Mouse (99%), Rat (98%), Zebrafish (93%), Xenopus laevis (91%), Pig (98%), Bovine (98%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Septin 2 is a filament-forming cytoskeletal GTPase
- Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin
- It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression
- During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation
- Septin 2 also plays a role in ciliogenesis and collective cell movements.