PIPA527213

NDRG1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA527213-Each-of-1 In Stock ₹ 48,905.50

PIPA527213 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

NDRG1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NDRG1

Gene Alias

CAP43; CMT4D; differentiation-related gene 1 protein; DRG1; DRG-1; GC4; HMSNL; Ndr1; Ndrg1; Ndrl; nickel-specific induction protein Cap43; NMSL; N-myc downstream regulated 1; N-myc downstream regulated gene 1; N-myc downstream-regulated gene 1 protein; Protein Ndr1; protein NDRG1; protein regulated by oxygen-1; PROXY1; Reducing agents and tunicamycin-responsive protein; Rit42; RTP; TARG1; TDD5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10397, 17988

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.67 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q62433, Q92597

Gene Symbols

NDRG1

Immunogen

Recombinant fragment corresponding to a region within amino acids 186 and 369 of Human NDRG1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, HepG2, NIH-3T3
  • Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (85%), Dog (98%), Bovine (98%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family
  • It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth and differentiation
  • Its defect causes Charcot-Marie-Tooth disease type 4D (CMT4D) that is characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes and hollow feet
  • NDRG1 plays a growth inhibitory role and serves as a marker of differentiation
  • It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon and the cells that border the lumen.