DREF Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527525-Each-of-1 | In Stock | ₹ 47,748.50 |
PIPA527525 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,748.50
GST (18%): ₹ 8,594.73
Total Price: ₹ 56,343.23
Antigen
DREF
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZBED1
Gene Alias
Ac-like transposable element; ALTE; BED-type zinc finger domain-containing protein 1; DNA replication-related element binding factor; DREF; dREF homolog; hDREF; KIAA0785; Putative Ac-like transposable element; TRAMP; ZBED1; Zinc finger BED domain-containing protein 1; zinc finger BED-type containing 1; zinc finger, BED-type containing 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9189
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O96006
Gene Symbols
ZBED1
Immunogen
Recombinant fragment corresponding to a region within amino acids 9 and 238 of Human DREF
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, Raji
- Predicted reactivity: Rhesus Monkey (99%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation
- RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells
- At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression
- Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.