GUK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527532-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA527532 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
GUK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GUK1
Gene Alias
AA409738; AL033299; AL033300; ATP:GMP phosphotransferase; ATP:GMP-phosphotransferase; AV026611; Gmk; GMP kinase; GMPK; Guanylate kinase; guanylate kinase 1; GUK; GUK1; Guk-1; RP11-520H14.2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2987
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 40% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q16774
Gene Symbols
GUK1
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 197 of Human Guanylate kinase
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T
- Predicted reactivity: Mouse (87%), Rat (87%), Rhesus Monkey (97%), Bovine (90%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Guanylate kinase (GK) catalyzes the ATP-dependent phosphorylation of GMP into GDP
- It is essential for recycling GMP and indirectly, cGMP
- In prokaryotes (such as Escherichia coli), lower eukaryotes (such as yeast) and in vertebrates, GK is a highly conserved monomeric protein of about 200 amino acids
- GK has been shown to be structurally similar to protein A57R (or SalG2R) from various strains of Vaccinia virus
- Proteins containing one or more copies of the DHR domain, an SH3 domain as well as a C-terminal GK-like domain, are collectively termed MAGUKs (membrane-associated guanylate kinase homologs) and include Drosophila lethal(1)discs large-1 tumor suppressor protein (gene dlg1); mammalian tight junction protein Zo-1; a family of mammalian synaptic proteins that seem to interact with the cytoplasmic tail of NMDA receptor subunits (SAP90/PSD-95, CHAPSYN-110/PSD-93, SAP97/DLG1 and SAP102); vertebrate 55 kD erythrocyte membrane protein (p55); C
- elegans protein lin-2; rat protein CASK; and human proteins DLG2 and DLG3
- There is an ATP-binding site (P-loop) in the N-terminal section of GK, which is not conserved in the GK-like domain of the above proteins
- However these proteins retain the residues known, in GK, to be involved in the binding of MP.