PIPA528199

MAPKAPK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528199-Each-of-1 In Stock ₹ 46,502.50

PIPA528199 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

MAPKAPK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAPKAPK3

Gene Alias

3PK; AI874665; chromosome 3p kinase; MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP3; MAPKAPK3; MAPKAP-K3; MAPKAPK-3; MapkKapk3; mitogen activated protein kinase-activated protein kinase 3; mitogen-activated protein kinase-activated protein kinase 3; MK3; MK-3; OTTHUMP00000210806; OTTHUMP00000210807

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

102626, 7867

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q16644, Q3UMW7

Gene Symbols

MAPKAPK3

Immunogen

Recombinant fragment corresponding to a region within amino acids 89 and 382 of Human MAPKAP Kinase 3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: H1299, HeLaS3, mouse spleen
  • Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (85%), Pig (98%), Chicken (93%), Rhesus Monkey (100%), Bovine (98%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses
  • MAPKAPK3 functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase
  • MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals
  • MAPKAPK3 was shown to be activated by growth inducers and stress stimulation of cells
  • In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses
  • MAPKAPK3 was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.