SLITRK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528646-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA528646 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SLITRK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SLITRK1
Gene Alias
3200001I04Rik; KIAA1910; Leucine-rich repeat-containing protein 12; LRRC12; RP11-395N17.1; SLIT and NTRK like family member 1; SLIT and NTRK-like family, member 1; SLIT and NTRK-like protein 1; slit and trk like gene 1; SLITRK1; Sltk1; TTM; UNQ233/PRO266
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
114798
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q96PX8
Gene Symbols
SLITRK1
Immunogen
Synthetic peptide corresponding to a region within amino acids 629 and 696 of Human SLITRK1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A549, HCT116
- Predicted reactivity: Rat (100%), Pig (100%), Rhesus Monkey (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- SLIT and NTRK-like family 1 (Slitrk1) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein
- These proteins are also homologous to trk neurotrophin receptors in their intracellular domains
- Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family
- For example, Slitrk1 is expressed primarily in mature neurons
- Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth
- While Slitrk1 variants have been suggested associated with Tourette's Syndrome, it is thought to play only a minor role if at all.