IP6K2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528681-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA528681 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
IP6K2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ip6k2
Gene Alias
1500005N04Rik; ATP:1D-myo-inositol-hexakisphosphate phosphotransferase; AW050208; Ihpk2; Inositol hexakisphosphate kinase 2; inositol hexaphosphate kinase 2; inositol-hexakisphosphate kinase; insp6 kinase 2; IP6 Kinase; IP6K2; P(i)-uptake stimulator; pi uptake stimulator; Pius; TCCCIA00113
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51447
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.51 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q9UHH9
Gene Symbols
Ip6k2
Immunogen
Recombinant fragment corresponding to a region within amino acids 171 and 426 of Human IP6K2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (82%), Rabbit (97%), Chicken (87%), Bovine (96%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The members of the inositol hexakisphosphate kinase family, IP6K1 and IP6K2, have a high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate
- IP6K1 and IP6K2 (also designated PiUS) convert InsP6 to PP-InsP5
- However, neither kinase demonstrates any catalytic activity with other inositol pyrophosphates
- The presence of InsP6, which inhibits serine/threonine protein phosphatases, increases the influx of calcium across the plasma membrane and implies that it may mediate the regulation of insulin exocytosis
- IP6K1 was purified as a 54 kDa protein in rat brain extracts
- By homology, IP6K1 and IP6K2 were characterized in mouse as a 50 kDa and 49 kDa protein, respectively
- IP6K1 displays ATP synthase activity by transferring a phosphate from PP-InsP5 to ADP, which suggests a role for the IP6 kinases as high energy phosphate donors.