mGluR3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528767-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA528767 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
mGluR3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRM3
Gene Alias
0710001G23Rik; G protein-coupled receptor, family C, group 1, member C; GLUR3; glutamate metabotropic receptor 3; glutamate receptor; glutamate receptor, metabotropic 3; Gprc1c; GRM3; M mGlu3; Metabotropic glutamate receptor 3; mGlu3; mGluR3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
108069, 24416, 2913
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.95 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P31422, Q14832, Q9QYS2
Gene Symbols
GRM3
Immunogen
Synthetic peptide corresponding to a region within amino acids 815 and 879 of Human mGluR-3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, mouse brain, rat brain
- Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Glutamate is the main excitatory neurotransmitter in the brain
- For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission
- Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins
- These receptors are called metabotropic glutamate receptors
- In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores
- Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase
- The Group-I receptors include mGluR1a and mGluR5
- The Group-II receptors in include mGluR2 and mGluR3.