Sortilin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529195-Each-of-1 | In Stock | ₹ 49,617.50 |
PIPA529195 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,617.50
GST (18%): ₹ 8,931.15
Total Price: ₹ 58,548.65
Antigen
Sortilin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Sort1
Gene Alias
100 kDa NT receptor; 2900053A11Rik; AI852375; Glycoprotein 110; glycoprotein 95; Gp110; Gp95; LDLCQ6; mNTR3; neurotensin receptor 3; NT3; NTR3; Nts3; Ntsr3; Sort1; Sortilin; sortilin 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20661, 6272, 83576
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
O54861, Q6PHU5, Q99523
Gene Symbols
Sort1
Immunogen
Recombinant fragment corresponding to a region within amino acids 462 and 716 of Human Sortilin 1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Mouse brain
- Predicted reactivity: Mouse (89%), Rat (90%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface
- Sortilin is required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR)
- It is also required for protein transport from the Golgi apparatus to the endosomes
- Sortilin promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB)
- Also, Sortilin acts as a receptor for neurotensin.