PIPA528837

NKG2C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528837-Each-of-1 In Stock ₹ 46,502.50

PIPA528837 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

NKG2C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KLRC2

Gene Alias

CD159 antigen-like family member C; CD159A; CD159c; cd159e; killer cell lectin like receptor C2; killer cell lectin-like receptor subfamily C, member 2; KLRC1; KLRC2; NK cell receptor C; NKG2; NKG2A; NKG2C; NKG2-C; NKG2-C type II integral membrane protein; NKG2-C-activating NK receptor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3822

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.56 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P26717

Gene Symbols

KLRC2

Immunogen

Synthetic peptide corresponding to a region within amino acids 1 and 45 of NKG2-C

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: K562
  • Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation
  • They can also regulate specific humoral and cell-mediated immunity
  • The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells
  • This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain
  • This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells
  • The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12
  • Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.