PNK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA528853-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA528853 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PNK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pnkp
Gene Alias
1810009G08Rik; 2'(3')-polynucleotidase; AOA4; bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; EIEE10; Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP); MCSZ; phosphatase/kinase; PKNP; PNK; PNKP; Polynucleotide 3'-phosphatase; Polynucleotide 5'-hydroxyl-kinase; polynucleotide kinase 3'- phosphatase; polynucleotide kinase 3'-phosphatase; polynucleotide kinase-3'-phosphatase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11284
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q96T60
Gene Symbols
Pnkp
Immunogen
Recombinant fragment corresponding to a region within amino acids 78 and 521 of Human PNK
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A549, HeLa, HepG2
- Predicted reactivity: Mouse (82%), Rat (81%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Anti-human Polynucleotide Kinase Mouse Monoclonal Antibody recognizes polynucleotide kinase (PNK), a 57 kDa nuclear enzyme implicated in DNA strand repair processes that occur during DNA replication and recombination, or in response to DNA damaging agents
- PNK targets the DNA 5'-hydroxy and 3'-phosphate termini for phosphorylation and dephosphorylation events
- During strand breakage in human cells, normal PNK associates with other nuclear proteins to prepare the DNA termini for the enzymatic actions of DNA polymerase-beta and DNA ligase III
- PNK is a key functional component in maintaining the genetic stability of human cells.