PIPA528892

GSTM5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528892-Each-of-1 In Stock ₹ 48,015.50

PIPA528892 - Each of 1

₹ 48,015.50

In Stock

Quantity

1

Base Price: ₹ 48,015.50

GST (18%): ₹ 8,642.79

Total Price: ₹ 56,658.29

Antigen

GSTM5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GSTM5

Gene Alias

fibrous sheath component 2; Fsc2; glutathione S-alkyltransferase M5; glutathione S-aralkyltransferase M5; glutathione S-aryltransferase M5; glutathione S-transferase M5; glutathione S-transferase Mu 5; glutathione S-transferase, mu 5; glutathione-S-transferase, mu 5; GST class-mu 5; Gstm3; GSTM5; GSTM5-5; GTM5; S-(hydroxyalkyl)glutathione lyase M5

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14866, 2949, 64352

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P46439, P48774, Q9Z1B2

Gene Symbols

GSTM5

Immunogen

Full length human GSTM5 Recombinant protein.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: mouse testis, rat testis
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families
  • At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta
  • This gene encodes a glutathione S-transferase that belongs to the mu class
  • The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione
  • The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic
  • These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs
  • Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.