PIPA528928

RNF20 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528928-Each-of-1 In Stock ₹ 46,502.50

PIPA528928 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

RNF20

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RNF20

Gene Alias

4833430L21Rik; AW540162; BRE1; BRE1 E3 ubiquitin ligase homolog; BRE1A; BRE1-A; C79397; E3 ubiquitin-protein ligase BRE1A; FLJ11189; FLJ20382; hBRE1; HNF3B; homolog of S. cerevisiae BRE1; hypothetical protein; KIAA2779; Kiaa4116; MGC129667; MGC129668; mKIAA4116; RCJMB04_5a23; RING finger protein 20; ring finger protein 20, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1A; Rnf20; TCF3B

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56254

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q5VTR2

Gene Symbols

RNF20

Immunogen

Recombinant fragment corresponding to a region within amino acids 246 and 502 of Human RNF20

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, H1299, HeLa, Molt-4, Raji
  • Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (81%), Chicken (93%), Rhesus Monkey (100%), Bovine (97%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B
  • RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS)
  • In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes
  • Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.