RAB5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529022-Each-of-1 | In Stock | ₹ 58,562.00 |
PIPA529022 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,562.00
GST (18%): ₹ 10,541.16
Total Price: ₹ 69,103.16
Antigen
RAB5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RAB5A
Gene Alias
2410015H04Rik; AI663973; AU021172; nnyRab5a; Rab 5; Rab 5A; RAB5; RAB5A; RAB5A, member RAS oncogene family; Ras related protein; RAS-associated protein RAB5A; ras-related protein Rab-5A; Small GTP-binding protein rab5
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
271457, 5868, 64633
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1.47 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
M0RC99, P20339, Q9CQD1
Gene Symbols
RAB5A
Immunogen
Synthetic peptide corresponding to a region within amino acids 132 and 215 of Human RAB5A
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: A431, Raji, mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%), Rhesus Monkey (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes
- Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion
- RAB5A is required for the fusion of plasma membranes and early endosomes
- Contributes to the regulation of filopodia extension
- Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan
- Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.