EEA1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529013-Each-of-1 | In Stock | ₹ 52,020.50 |
PIPA529013 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,020.50
GST (18%): ₹ 9,363.69
Total Price: ₹ 61,384.19
Antigen
EEA1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
EEA1
Gene Alias
A430109M19Rik; B230358H09Rik; Early endosome antigen 1; early endosome antigen 1, 162kD; early endosome-associated protein; EEA1; Endosome-associated protein p162; MST105; MSTP105; ZFYVE2; Zinc finger FYVE domain-containing protein 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
216238, 314764, 8411
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
Q15075, Q8BL66
Gene Symbols
EEA1
Immunogen
Synthetic peptide corresponding to a region within amino acids 1342 and 1411 of Human EEA1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Hamster, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: HepG2, A375, mouse brain, PC-12, Rat-2, A549, MNT-1
- Predicted reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Early endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles
- Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations
- Zinc-finger-like domains, reminiscent of those found in nucleic acid binding proteins, are located in the amino and carboxyl-terminal domains of EEA1
- The carboxyl-terminal zinc-finger-like-domain is conserved in several other non-nuclear proteins, some of which are also involved in intracellular protein trafficking
- In addition, this domain is an authentic zinc-binding domain and is critical to the intracellular localization of EEA1
- Membrane association of EEA1 has been shown dependent on phosphatidyl 3-kinase activity, inhibitors of which cause EEA1 to dissociate from early endosomes.