PIPA529516

alanyl-tRNA Synthetase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529516-Each-of-1 In Stock ₹ 46,057.50

PIPA529516 - Each of 1

₹ 46,057.50

In Stock

Quantity

1

Base Price: ₹ 46,057.50

GST (18%): ₹ 8,290.35

Total Price: ₹ 54,347.85

Antigen

alanyl-tRNA Synthetase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AARS1

Gene Alias

Aars; AI316495; alanine tRNA ligase 1, cytoplasmic; alanine--tRNA ligase, cytoplasmic; alanine--tRNA ligase, cytoplasmic {ECO:0000255; Alanyl-tRNA synthetase; alanyl-tRNA synthetase {ECO:0000255; alanyl-tRNA synthetase, cytoplasmic; alaRS; alaRS {ECO:0000255; C76919; CMT2N; EIEE29; HAMAP-Rule:MF_03133}; Protein sticky; Renal carcinoma antigen NY-REN-42; sti

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16, 234734

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.23 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P49588, Q8BGQ7

Gene Symbols

AARS1

Immunogen

Recombinant fragment corresponding to a region within amino acids 461 and 723 of Human alanyl-tRNA synthetase

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, H1299, HeLa, HepG2, mouse liver
  • Predicted reactivity: Mouse (95%), Rat (92%), Xenopus laevis (84%), Chicken (86%), Bovine (92%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes
  • Class II tRNA synthases evolved early in evolution and are highly conserved
  • This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E
  • coli protein
  • tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons
  • They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.