PIPA530145

RARS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA530145-Each-of-1 In Stock ₹ 53,578.00

PIPA530145 - Each of 1

₹ 53,578.00

In Stock

Quantity

1

Base Price: ₹ 53,578.00

GST (18%): ₹ 9,644.04

Total Price: ₹ 63,222.04

Antigen

RARS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RARS1

Gene Alias

2610011N19Rik; 2610037E21Rik; AL033339; arginine tRNA ligase 1, cytoplasmic; arginine--tRNA ligase, cytoplasmic; Arginyl-tRNA synthetase; arginyl-tRNA synthetase, cytoplasmic; argRS; AW985894; DALRD1; HLD9; MGC8641; RARS

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5917

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P54136

Gene Symbols

RARS1

Immunogen

Recombinant fragment corresponding to a region within amino acids 170 and 458 of Human Arginyl tRNA synthetase

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, H1299, HeLa, HepG2
  • Predicted reactivity: Mouse (90%), Rat (90%), Pig (90%), Chicken (83%), Rhesus Monkey (97%), Chimpanzee (100%), Bovine (93%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases
  • ArgRS (Arginyl-tRNA synthetase), also known as RARS or DALRD1, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS, ValRS and IleRS
  • These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid
  • ArgRS localizes to the cytoplasm and exists as a monomer but can also associate with other tRNA synthetases and auxiliary proteins to form a multisubunit complex
  • In the presence of ATP, arginine (Arg) and tRNA, ArgRS joins Arg to tRNA(Arg) at its synthetic active site
  • Two cytoplasmic forms of ArgRS have been described in mammals, differing by the addition of a 73 amino acid sequence that is required for ArgRS assembly into the multisubunit complex.