THRB Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA529684-Each-of-1 | In Stock | ₹ 51,620.00 |
PIPA529684 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,620.00
GST (18%): ₹ 9,291.60
Total Price: ₹ 60,911.60
Antigen
THRB
Classification
Polyclonal
Conjugate
Unconjugated
Gene
THRB
Gene Alias
c-erbA-2; c-erbAbeta; C-ERBA-BETA; ERBA 2; ERBA BETA; ERBA2; ERBA-BETA; fj24f03; GRTH; LOW QUALITY PROTEIN: thyroid hormone receptor beta; MGC126109; MGC126110; NR1A2; Nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; RATT3REC; si:ch211-264a6.2; T3R[b]; T3Rbeta; T3rec; THR; THR1; thr2; Thrb; Thrb1; Thrb2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor beta; thyroid hormone receptor beta 1; thyroid hormone receptor beta 2; thyroid hormone receptor beta 3; thyroid hormone receptor beta1; thyroid hormone receptor beta-1; thyroid hormone receptor beta2; thyroid hormone receptor beta2delta; thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2); thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); TR; TR beta; TR beta 1; TR[b]1; trb; TR-B1C-ERBA-2; TRbeta; TR-beta; TRbeta1; TRbeta2Delta; wu:fj24f03
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21834, 24831, 7068
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.76 mg/mL
Formulation
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P10828, P18113, P37242
Gene Symbols
THRB
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 199 of Human Thyroid Hormone Receptor beta
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (93%), Rat (92%), Sheep (90%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Thyroid hormone receptors (TR), also known as c-erbA-2, are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences called hormone response elements following activation by the appropriate hormone
- Thyroid hormones, through their interaction with TR, effect metabolic processes, growth and development in many tissues by regulating the expression of genes for growth hormone, malic enzyme and several hepatic proteins
- There are two forms of TR; TR alpha (on chromosome 17) and TR beta (on chromosome 3)
- Each of these isoforms also has two isoforms; TR alpha-1 and TRv alpha-2, and TR beta-1 and TR beta-2 respectively
- TR alpha-1 and 2 are identical through amino acid 370 where their sequences diverge
- TRv alpha-2, which does not bind T3 and is a strong negative regulator of the functional TR, is 80 amino acids longer than TR alpha-1
- The corresponding gene for the thyroid hormone receptor beta-1 is NR1A2.