PIPA529775

GDF5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529775-Each-of-1 In Stock ₹ 48,015.50

PIPA529775 - Each of 1

₹ 48,015.50

In Stock

Quantity

1

Base Price: ₹ 48,015.50

GST (18%): ₹ 8,642.79

Total Price: ₹ 56,658.29

Antigen

GDF5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GDF5

Gene Alias

BDA1C; Bmp14; BMP-14; Bone morphogenetic protein 14; bp; brachypodism; brp; Cartilage-derived morphogenetic protein 1; cartilage-derived morphogenetic protein-1; CDMP1; Cdmp-1; GDF5; GDF-5; growth differentiation factor 5; growth/differentiation factor 5; H-GDF-5; LAP4; LAP-4; Lipopolysaccharide-associated protein 4; LPS-associated protein 4; OS5; radotermin; SYM1B; SYNS2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8200

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.65 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P43026

Gene Symbols

GDF5

Immunogen

Recombinant fragment corresponding to a region within amino acids 169 and 501 of Human GDF5

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: IMR32
  • Predicted reactivity: Human (99%), Mouse (96%), Pig (98%), Rabbit (98%), Chicken (83%), Bovine (97%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage
  • Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities
  • The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond
  • Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino acid signal peptide and a 354 amino acid propeptide
  • This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease.