PIPA529782

GDF15 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA529782-Each-of-1 In Stock ₹ 52,866.00

PIPA529782 - Each of 1

₹ 52,866.00

In Stock

Quantity

1

Base Price: ₹ 52,866.00

GST (18%): ₹ 9,515.88

Total Price: ₹ 62,381.88

Antigen

GDF15

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Gdf15

Gene Alias

Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9518

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q99988

Gene Symbols

Gdf15

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 308 of Human GDF-15

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: 293T, A431, HeLa
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs
  • GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues
  • The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development
  • GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway
  • Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.