PIPA530078

L-Plastin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA530078-Each-of-1 In Stock ₹ 46,591.50

PIPA530078 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

L-Plastin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

LCP1

Gene Alias

65 kDa macrophage protein; AW536232; bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); cb245; CP64; D14Ertd310e; DKFZp781A23186; epididymis secretory protein Li 37; fj24b12; FLJ25423; FLJ26114; FLJ39956; HEL-S-37; LC64P; LCP1; LCP-1; leucocyte-specific plastin 1; L-fimbrin; LPL; L-plastin; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65); L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P); lymphocyte cytosolic plastin 1; lymphocyte cytosolic protein 1; lymphocyte cytosolic protein 1 (L-plastin); Lymphocyte cytosolic protein-1 (plasmin); plastin 2; plastin 2, L; plastin-2; Pls2; pp65; wu:fj24b12

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3936

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.4 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P13796

Gene Symbols

LCP1

Immunogen

Recombinant protein fragment corresponding to a region within amino acids 328 and 598 of Human L-Plastin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: A431, Jurkat, Raji
  • Predicted reactivity: Human (99%), Mouse (95%), Rat (94%), Zebrafish (84%), Xenopus laevis (89%), Chicken (90%), Rhesus Monkey (99%), Bovine (95%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins
  • It has two actin-binding domains and two EF hand type calcium-binding domains
  • It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli
  • It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes
  • L-plastin is expressed in majority of human cancer cell lines derived from solid tumors
  • Its expression is positively upregulated by testosterones in androgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.