PCBP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530116-Each-of-1 | In Stock | ₹ 53,044.00 |
PIPA530116 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,044.00
GST (18%): ₹ 9,547.92
Total Price: ₹ 62,591.92
Antigen
PCBP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PCBP2
Gene Alias
Alpha CP2; Alpha-CP2; alphaCP-2; AW412548; CBP; CTBP; fb36h02; Heterogeneous nuclear ribonucleoprotein E2; heterogeneous nuclear ribonucleoprotein X; heterogenous nuclear ribonucleoprotein E2; hnRNP E2; hnRNP X; HNRNPE2; hnRNP-E2; Hnrnpx; HNRPE2; Hnrpx; MGC110998; Pcbp2; pcbp2 protein; PCBP3; poly(rC) binding protein 2; poly(rC)-binding protein 2; Putative heterogeneous nuclear ribonucleoprotein X; rCbinding protein 2; wu:fb36h02; zgc:55964
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18521, 5094
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1.03 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
Q15366, Q61990
Gene Symbols
PCBP2
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 85 and 365 of Human PCBP2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: Jurkat, Raji, K562, NCI-H929
- Predicted reactivity: Mouse (100%), Rat (97%), Pig (91%), Bovine (93%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The protein encoded by this gene appears to be multifunctional
- Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins
- The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding
- Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure
- It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA
- The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability
- This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2
- This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes
- This gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2)
- Multiple transcript variants encoding different isoforms have been found for this gene.