PIPA530248

CNOT3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA530248-Each-of-1 In Stock ₹ 49,350.50

PIPA530248 - Each of 1

₹ 49,350.50

In Stock

Quantity

1

Base Price: ₹ 49,350.50

GST (18%): ₹ 8,883.09

Total Price: ₹ 58,233.59

Antigen

CNOT3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CNOT3

Gene Alias

A930039N10Rik; CCR4-associated factor 3; CCR4-NOT transcription complex subunit 3; CCR4-NOT transcription complex, subunit 3; CNOT3; KIAA0691; LENG2; Leukocyte receptor cluster member 2; Not3; NOT3 (negative regulator of transcription 3, yeast) homolog; NOT3H

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4849

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.63 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

O75175

Gene Symbols

CNOT3

Immunogen

Recombinant fragment corresponding to a region within amino acids 522 and 753 of Human CNOT3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: NT2D1, IMR32, Jurkat, HeLa
  • Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (92%), Rabbit (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation
  • Additional complex functions may be a consequence of its influence on mRNA expression
  • May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism
  • Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA
  • Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases
  • Involved in the maintenance of embryonic stem (ES) cell identity
  • [UniProt]