PIPA528130

ATF7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528130-Each-of-1 In Stock ₹ 47,481.50

PIPA528130 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

ATF7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATF7

Gene Alias

1110012F10Rik; 9430065F09Rik; activating transcription factor 7; AI549878; ATF7; ATFA; C130020M04Rik; cAMP-dependent transcription factor ATF-7; Cyclic AMP-dependent transcription factor ATF-7; MGC57182; transcription factor ATF-A

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11016

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.88 mg/mL

Formulation

PBS with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P17544

Gene Symbols

ATF7

Immunogen

Synthetic peptide corresponding to a region within amino acids 432 and 494 of Human ATF7

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HepG2, Raji
  • Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Plays important functions in early cell signaling
  • Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters
  • Activator of the NF-ELAM1/delta-A site of the E-selectin promoter
  • Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers
  • Also can bind TRE promoter sequences when heterodimerized with members of the JUN family
  • Isoform 4/ATF-A0acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter
  • Isoform 5/ATF-4acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities
  • It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.