Grancalcin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA530497-Each-of-1 | In Stock | ₹ 47,481.50 |
PIPA530497 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Grancalcin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Gca
Gene Alias
5133401E04Rik; AI573844; Gca; GCL; grancalcin; grancalcin, EF-hand calcium binding protein; grancalcin, EF-hand calcium-binding protein; grancalcin, penta-EF-hand protein; null
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25801
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.99 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P28676
Gene Symbols
Gca
Immunogen
Recombinant fragment corresponding to a region within amino acids 7 and 217 of Human Grancalcin
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7
- Predicted reactivity: Mouse (88%), Rat (87%), Xenopus laevis (81%), Rhesus Monkey (93%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- This gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages
- It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2
- Grancalcin localization is dependent upon calcium and magnesium
- In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation.